Carboxylation

Carboxylation is a highly versatile method for fixing carbon dioxide (CO2), a crucial transformation with significant implications for advancing capture technologies and fostering a sustainable industry. The carboxylic acids and derivatives produced through this process hold considerable interest across various sectors, including pharmaceuticals and polymers.
However, most of these chemicals are currently derived from non-renewable resources, highlighting the need to develop sustainable pathways for their synthesis. One major challenge in carboxylation is the activation of CO2, which is hindered by its high oxidation state and linear configuration. To overcome this hurdle, various approaches have been explored, including photochemical, electrochemical, enzymatic, and thermochemical methods. While these methods have shown promising results, substantial efforts are still needed to scale them up for industrial applications.