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Diglycidyl ether

CAS#[2238-07-5]
G-codeGEO-04380
EC number218-802-6
Molecular formulaC6H10O3
Molecular weight130.14
Synonyms

Bis(2,3-epoxypropyl)ether ; 2,2'-[Oxybis(methylene)]bisoxirane ; 2-(Oxiran-2-ylmethoxymethyl)oxirane ; 2-(Glycidoxymethyl)oxirane

Structure of Diglycidyl ether
General description

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Regulatory Information

CORROSIVE LIQUID, TOXIC, N.O.S. UN2922 8 (6.1)/ PG III

GHS pictogram
GHS05_corrosiveGHS06_toxic
Signal WordDanger
Hazard Statements
H302 - H312 - H314 - H330

H302 – Harmful if swallowed
H312 – Harmful in contact with skin
H314 – Causes severe skin burns and eye damage
H330 – Fatal if inhaled

Precautionary Statements
P280 - P301+330+331 - P310 - P305+351+338 - P304+340 - P302+352

P280 – Wear protective gloves/protective clothing/eye protection/face protection:
P310 – Immediately call a POISON CENTER or doctor/physician:
P301+330+331 – IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P302+352 – IF ON SKIN: Wash with soap and water
P304+340 – IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P305+351+338 – IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing

Product categorization

Description

Diglycidyl ether it is used as a reactive diluent for epoxy resin, as a chemical intermediate, stabilizer of chlorinated organic compounds…

Show full description

General description of Diglycidyl ether:

Structure of Diglycidyl ether

Diglycidyl ether (DGE) [2238-07-5], bis-(2,3-epoxypropyl)ether or 2,2′-[oxybis(methylene)]bis(oxirane) is a colorless liquid with an irritant odour and a boiling point of 220 °C.[1] It is miscible with water and common organic solvents. This compound is toxic and can prove fatal or cause permanent damage if inhaled LC50 = 30 ppm/4 h, mouse) or consumed orally (LD50 = 170 mg/kg, mouse).[2] It is highly reactive as other epoxides and it can polymerize violently in the presence of catalysts or when heated. Diglycidyl ether is usually prepared from epichlorohydrin by refluxing with sodium hydroxide in toluene.[3]

Application of Diglycidyl ether:

It is used as a reactive diluent for epoxy resin, as a chemical intermediate, stabilizer of chlorinated organic compounds and as a textile-treating agent. Considering this class of compounds, there are several commercially substances available with much lower toxicity profile, such as Bisphenol A diglycidyl ether.[4]

Product categorization (Chemical groups):

Main category: Second level: Third level: ______________________________________________________________________________________
[1]  C. H. Hine, J. K. Kodama, R. J. Guzman, M. K. Dunlap, R. Lima, G. S. Loquvam Arch. Environ. Health 1961, 2, 31. [2]  C. H. Hine, J. K. Kodama, H. H. Anderson, D. W. Simonson, J. S. Wellington Arch. Indust. Health 1958, 2, 129. [3]  W. H. Machleder, J. M. Bollinger Multipurpose hydrocarbon fuel and lubricating oil additive, US4259086 (A) 1981, Rohm & Haas company. [4]  N. A. M. Berdasco, J. M. Waechter Jr. Epoxy Compounds: Aromatic Diglycidyl Ethers, Polyglycidyl Ethers, Glycidyl Esters, and Miscellaneous Epoxy Compounds in Patty’s Toxicology 2012, Sixth Edition, vol. 4, John Wiley & Sons, Inc..

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