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Sulfides / Thiols


Sulfides or thioethers are a class of organic compounds that contain C-S-C linkage while thiols are sulfur analogues of alcohols. Many thiols have strong odours resembling that of garlic or rotten eggs. Sulfides are typically prepared by alkylation of thiols. Alternatively, they can be synthesized by the addition of a thiol to an alkene (thiol-ene reaction). Sulfides can be easily oxidized to sulfoxides, which can themselves be further oxidized to sulfones. They are readily alkylated to give stable sulfonium salts. Sulfides bind to metals to form thioether complexes or they can undergo reductive dealkylation in the presence of certain metals. Thiols can be prepared from alkyl halides via an S-alkylation of thiourea or sodium hydrosulfide. Thiolates are more potent nucleophiles than the corresponding alkoxides. As the functional group of the cysteine, it plays a very important role in biology, many cofactors feature thiols. Many commercial drugs also contain thiol group.

Product nameStructureCAS#G-code
New2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-ethanethiolStructure of 2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-ethanethiol[76855-57-7]GEO-04479
New(4-Bromophenyl)diphenylsulfonium triflateStructure of (4-Bromophenyl)diphenylsulfonium triflate[255056-44-1]GEO-04499
6-(Methylthio)pyrimido[5,4-d]pyrimidin-4(1H)-oneStructure of 6-(Methylthio)pyrimido[5,4-d]pyrimidin-4(1H)-one[98550-19-7]GEO-04340
4-Cyclopentylamino-2-methanethiopyrimidine-5-carboxylic acid ethyl ester[211245-62-4]GEO-04295
Cyanomethyl-2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside[61145-39-9]GEO-04234
Benzene-1,4-dithiolStructure of Benzene-1,4-dithiol[624-39-5]GEO-04155
5-Bromo-1,3-benzenedithiolStructure of 5-Bromo-1,3-benzenedithiol[1219501-75-3]GEO-04125
2-Bromo-4-fluoro-1-(methylthio)benzeneStructure of 2-Bromo-4-fluoro-1-(methylthio)benzene[91524-70-8]GEO-04054
4,6-Dihydro-1H,3H-thieno[3,4-c]furan-1,3-dione[75532-25-1]GEO-04022
2,5-Dihydrothiophene-3,4-dicarboxylic acid[20688-07-7]GEO-04023
Dimethyl 2,5-dihydrothiophene-3,4-dicarboxylate[20946-32-1]GEO-04024
2-(tert-Butyl)benzenethiolStructure of 2-(tert-Butyl)benzenethiol[19728-41-7]GEO-04077
4-Benzylthio-1H-pyrazoleStructure of 4-Benzylthio-1H-pyrazole[308121-87-1]GEO-04063
3,4-(Methylenedioxy)thiophenolStructure of 3,4-(Methylenedioxy)thiophenol[5274-08-8]GEO-03999
1,3-BenzenedithiolStructure of 1,3-Benzenedithiol[626-04-0]GEO-03897
4-(Methylthio)phenylacetic acidStructure of 4-(Methylthio)phenylacetic acid[16188-55-9]GEO-01963
4,6-Diamino-2-mercaptopyrimidine[1004-39-3]GEO-00921
3-(Methylthio)propanoic acidStructure of 3-(Methylthio)propanoic acid[646-01-5]GEO-01970
1-(Dimethylamino)-2-propanethiol[1920-46-3]GEO-03732
2-(Dimethylamino)-1-propanethiol[66338-45-2]GEO-03243
3-(Dimethylamino)-1-propanethiol hydrochlorideStructure of 3-(Dimethylamino)-1-propanethiol hydrochloride[38048-81-6]GEO-03245
2-(Dimethylamino)-1-propanethiol hydrochloride[101724-24-7]GEO-03244
2-Methylthio-4-aminouracilStructure of 2-Methylthio-4-aminouracil[1195219-77-2]GEO-03079
3,5-Dichlorobenzenemethanethiol[65963-17-9]GEO-03033
6-Methyl-2-methylsulfanyl-1H-pyrimidin-4-oneStructure of 6-Methyl-2-methylsulfanyl-1H-pyrimidin-4-one[6328-58-1]GEO-02802
5-Chloro-3-methylmercapto-1,2,4-thiadiazoleStructure of 5-Chloro-3-methylmercapto-1,2,4-thiadiazole[21735-15-9]GEO-02726
(R)-2-Methylcysteine hydrochlorideStructure of (R)-2-Methylcysteine hydrochloride[148766-37-4]GEO-02622
(3-Fluorophenyl)methanethiol[40096-23-9]GEO-01429
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate[5909-24-0]GEO-01330
3-(Methylthio)phenyl isocyanateStructure of 3-(Methylthio)phenyl isocyanate[28479-19-8]GEO-01964
4-(Methylthio)phenyl isocyanateStructure of 4-(Methylthio)phenyl isocyanate[1632-84-4]GEO-01965
3-(Methylthio)phenyl isothiocyanateStructure of 3-(Methylthio)phenyl isothiocyanate[51333-80-3]GEO-01966
5-(Pyridin-2-ylthio)furan-2-carbaldehyde[709635-68-7]GEO-03484
(Z)-Methyl 2-cyano-3-(5-(pyridin-2-ylthio)furan-2-yl)acrylateN/AGEO-03485
(Z)-2-Isocyano-3-(5-(pyridin-2-ylthio)furan-2-yl)acrylonitrileN/AGEO-03486
2-Chloro-6-methylthiophenol[18858-05-4]GEO-00733
4-(Trifluoromethoxy)phenylmethanethiolStructure of 4-(Trifluoromethoxy)phenylmethanethiol[175278-03-2]GEO-02375
Dimethyl 2,6-dimethyl-4-(5-(pyridin-2-ylthio)furan-2-yl)-1,4-dihydropyridine-3,5-dicarboxylateN/AGEO-03494
5,6-Dihydro-1,4-dithiin-2,3-dicarboximideStructure of 5,6-Dihydro-1,4-dithiin-2,3-dicarboximide[24519-85-5]GEO-01089
3-(Trifluoromethyl)phenylmethanethiolStructure of 3-(Trifluoromethyl)phenylmethanethiol[25697-55-6]GEO-02383
2-(Trifluoromethyl)phenylmethanethiolStructure of 2-(Trifluoromethyl)phenylmethanethiol[26039-98-5]GEO-02382
4-(Trifluoromethyl)phenylmethanethiolStructure of 4-(Trifluoromethyl)phenylmethanethiol[108499-24-7]GEO-02384
5-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-carbaldehydeN/AGEO-03520
Dimethyl 2,6-dimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-1,4-dihydropyridine-3,5-dicarboxylateN/AGEO-03522
2-((5-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)methylene)malononitrileN/AGEO-03523
(3-Chlorophenyl)methanethiol[25697-57-8]GEO-00766
(3,4-Difluorophenyl)methanethiol[666752-97-2]GEO-01068
2,7,7-Trimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03524
(E)-Methyl 2-cyano-3-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)acrylateN/AGEO-03525
(E)-3-(5-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)acrylic acidN/AGEO-03526
3,3,6,6-Tetramethyl-9-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dioneN/AGEO-03528
(2,5-Difluorophenyl)methanethiolN/AGEO-01067
Cyclohexene sulfide[286-28-2]GEO-00868
Diethyl 2,6-dimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-1,4-dihydropyridine-3,5-dicarboxylateN/AGEO-03540
(2,4-Difluorophenyl)methanethiol[170924-51-3]GEO-01066
5-Methylthio-1,3,4-thiadiazole-2-thiolStructure of 5-Methylthio-1,3,4-thiadiazole-2-thiol[6264-40-0]GEO-01973
Ethyl 2,7,7-trimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylateN/AGEO-03545
2,3-Dihydro-1,4-dithiino[2,3-c]furan-5,7-dione[10489-75-5]GEO-01087
4,5-Diphenyl-2-imidazolethiol[2349-58-8]GEO-01241
1,2-BenzenedithiolStructure of 1,2-Benzenedithiol[17534-15-5]GEO-00251
PhenylthiotrimethylsilaneStructure of Phenylthiotrimethylsilane[4551-15-9]GEO-02142
2-Mercapto-6-nitrobenzothiazoleStructure of 2-Mercapto-6-nitrobenzothiazole[4845-58-3]GEO-01654
(2-Pyrimidylthio)acetic acidStructure of (2-Pyrimidylthio)acetic acid[88768-45-0]GEO-02198
2-Chloroethyl ethyl sulfideStructure of 2-Chloroethyl ethyl sulfide[693-07-2]GEO-03411
6-Hydroxy-2-mercaptopurineStructure of 6-Hydroxy-2-mercaptopurine[2487-40-3]GEO-01523
2-Amino-5-(ethylthio)-1,3,4-thiadiazoleStructure of 2-Amino-5-(ethylthio)-1,3,4-thiadiazole[25660-70-2]GEO-00136
6-Amino-2-mercaptobenzothiazoleStructure of 6-Amino-2-mercaptobenzothiazole[7442-07-1]GEO-00151
4-Amino-2-mercaptopyrimidineStructure of 4-Amino-2-mercaptopyrimidine[333-49-3]GEO-00152
4′-(Methylthio)acetophenoneStructure of 4'-(Methylthio)acetophenone[1778-09-2]GEO-01947
2-Methylthio-2-imidazoline hydriodideStructure of 2-Methylthio-2-imidazoline hydriodide[5464-11-9]GEO-01949
5-tert-Butyl-2-hydroxy-3-(methylthio)benzaldehydeStructure of 5-tert-Butyl-2-hydroxy-3-(methylthio)benzaldehyde[81322-70-5]GEO-02513
2-Amino-5-(methylthio)-1,3,4-thiadiazoleStructure of 2-Amino-5-(methylthio)-1,3,4-thiadiazole[5319-77-7]GEO-00174
(2-Fluorophenyl)methanethiol[72364-46-6]GEO-01428
(4-Fluorophenyl)methanethiol[15894-04-9]GEO-01430