Cyclohexanemethanol – general description and application
General description of Cyclohexanemethanol:
Cyclohexanemethanol (CM), or (hydroxymethyl)cyclohexane, or cyclohexylcarbinol [100-49-2] is six-membered alicyclic organic compound that belong to alcohols. In its pure form, it is colorless viscious highly flammable liquid with the boiling point of 179-180 °C. It is insoluble in water and soluble in common organic solvents. CM is a non-corrosive and quick volatilize liquid with the LD50 = 250 mg/kg (mouse, intraperitoneal).
Convenient laboratory preparation starts with chlorocyclohexane that is converted to cyclohexylmagnesium chloride, which reacts with formaldehyde or paraformaldehyde.
Application of Cyclohexanemethanol:
Cyclohexanemethanol is usually used as a reagent in organic synthesis. It acts as a nucleohpile in highly beta-selective glucosidation of ethylthioglucosides. It can be used as a starting material for the synthesis of cyclohexanecarboxaldehyde, cyclohexanecarboxylic acid, cyclohexanone, and 1,4-cyclohexadione by photocatalytic oxidation using titanium dioxide nanoparticles. Cyclohexanemethanol can be biologically oxidized by the yeasts Candida maltosa and Trichosporon mucoides under laboratory conditions.
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible materials are Strong oxidizing agents, Acid chlorides, Acid anhydrides. Excess heat. Keep away from open flames, hot surfaces and sources of ignition. Hazardous Combustion Products: Carbon monoxide (CO), Carbon dioxide (CO2). Cyclohexanemethanol is stable under normal conditions
Product categorization (Chemical groups):
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