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Nitriles


Nitriles are a class of organic compounds that contain at least one nitrile (cyano) function group. The main methods for producing nitriles in industry are ammoxidation and hydrocyanation. Other common preparations involve reactions of organic halides with cyanide salts, dehydration of aldoximes and amides, Sandmeyer reaction of aromatic diazonium salts. Nitrile groups in organic compounds can undergo a variety of reactions such as hydrolysis to first give carboxamides and then carboxylic acids, reduction to amines and alkyl nitriles can be deprotonated to nitrile anions that can alkylate a wide range of electrophiles. They also undergo nucleophilic addition reactions with organozinc compounds (Blaise reaction), alcohols (Pinner reaction) and amines. They are found in many useful compounds, including methyl cyanoacrylate in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves.

Product nameStructureCAS#G-code
5-Acetyl-2-amino-4-(2-furanyl)-6-methyl-4H-pyran-3-carbonitrileStructure of 5-Acetyl-2-amino-4-(2-furanyl)-6-methyl-4H-pyran-3-carbonitrile[105263-08-9]GEO-00016
5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrileStructure of 5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile[105263-07-8]GEO-00017
New5-Acetyl-2-amino-6-methyl-4-phenyl-4H-pyran-3-carbonitrileStructure of 5-Acetyl-2-amino-6-methyl-4-phenyl-4H-pyran-3-carbonitrile[89809-89-2]GEO-00018
2-Amino-5-chlorobenzonitrileStructure of 2-Amino-5-chlorobenzonitrile[5922-60-1]GEO-00097
5-Amino-4-cyano-3-cyanomethylpyrazoleStructure of 5-Amino-4-cyano-3-cyanomethylpyrazole[54711-21-6]GEO-00107
2-Amino-4-cyanopyridineStructure of 2-Amino-4-cyanopyridine[42182-27-4]GEO-03415
5-Amino-3-phenyl-isothiazole-4-carbonitrileStructure of 5-Amino-3-phenyl-isothiazole-4-carbonitrile[88009-93-2]GEO-03690
1,2,4,5-BenzenetetracarbonitrileStructure of 1,2,4,5-Benzenetetracarbonitrile[712-74-3]GEO-00253
(2-Benzimidazolyl)acetonitrileStructure of (2-Benzimidazolyl)acetonitrile[4414-88-4]GEO-00258
(2E)-3-[2,2′-Bithiophen]-5-yl-2-cyano-2-propenoic acidStructure of (2E)-3-[2,2'-Bithiophen]-5-yl-2-cyano-2-propenoic acid[2138319-65-8]GEO-04262
3′-Bromo-2,6-dimethyl-1,4-dihydro-[4,4′-bipyridine]-3,5-dicarbonitrileN/AGEO-03570
2-(5-Bromo-2-fluorobenzylidene)malononitrileStructure of 2-(5-Bromo-2-fluorobenzylidene)malononitrile[]GEO-03627
(E)-3-(5-Bromo-2-fluorophenyl)-2-cyanoacrylic acidStructure of (E)-3-(5-Bromo-2-fluorophenyl)-2-cyanoacrylic acid[]GEO-03632
4-(5-Bromo-2-fluorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrileStructure of 4-(5-Bromo-2-fluorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile[]GEO-03619
(E)-3-(5-(4-Bromo-2-fluorophenyl)furan-2-yl)-2-cyanoacrylic acidStructure of (E)-3-(5-(4-Bromo-2-fluorophenyl)furan-2-yl)-2-cyanoacrylic acid[]GEO-03638
4-(5-(4-Bromo-2-fluorophenyl)furan-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrileStructure of 4-(5-(4-Bromo-2-fluorophenyl)furan-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile[]GEO-03637
4-(5-Bromo-2-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileStructure of 4-(5-Bromo-2-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile[]GEO-03622
4-Bromo-1H-pyrazole-3-carbonitrileStructure of 4-Bromo-1H-pyrazole-3-carbonitrile[288246-16-2]GEO-00562
4-(3-Bromopyridin-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03569
5-Bromothiophene-2-carbonitrileStructure of 5-Bromothiophene-2-carbonitrile[2160-62-5]GEO-04253
2-((4-Bromothiophen-3-yl)methylene)malononitrileStructure of 2-((4-Bromothiophen-3-yl)methylene)malononitrile[]GEO-03663
3-n-ButoxypropionitrileStructure of 3-n-Butoxypropionitrile[6959-71-3]GEO-00607
4-(4-(tert-Butyl)phenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03604
2-Chloro-4-iodo-3-pyridinecarbonitrile[1171919-75-7]GEO-03264
2-((2-Chloro-4-iodopyridin-3-yl)methylene)malononitrileStructure of 2-((2-Chloro-4-iodopyridin-3-yl)methylene)malononitrile[]GEO-03645
3-Chloroisonicotinonitrile[68325-15-5]GEO-03482
2-Chloro-3-methoxybenzonitrileStructure of 2-Chloro-3-methoxybenzonitrile[853331-52-9]GEO-04562
2-(3-Chloro-4-methoxybenzylidene)malononitrileN/AGEO-03596
(E)-3-(3-Chloro-4-methoxyphenyl)-2-cyanoacrylic acidStructure of (E)-3-(3-Chloro-4-methoxyphenyl)-2-cyanoacrylic acid[]GEO-03618
4-(3-Chloro-4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrileStructure of 4-(3-Chloro-4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile[]GEO-03614
2-((5-(3-Chloro-4-methoxyphenyl)furan-2-yl)methylene)malononitrileStructure of 2-((5-(3-Chloro-4-methoxyphenyl)furan-2-yl)methylene)malononitrile[]GEO-03642
4-(3-Chloro-4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileStructure of 4-(3-Chloro-4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile[]GEO-03613
3-Chloro-4-methylbenzonitrileStructure of 3-Chloro-4-methylbenzonitrile[21423-81-4]GEO-04031
2-Chloro-6-methylbenzonitrileStructure of 2-Chloro-6-methylbenzonitrile[6575-09-3]GEO-00710
2-Chlorothiazole-5-carbonitrile[51640-36-9]GEO-03608
5-ChlorovaleronitrileStructure of 5-Chlorovaleronitrile[6280-87-1]GEO-00825
N-Cyanoacetylurethane[6629-04-5]GEO-00827
4-Cyanobenzenesulfonyl chloride[49584-26-1]GEO-04025
(E)-2-Cyano-3-(2-(dimethylamino)-6-fluoro-4-methoxyphenyl)acrylic acidN/AGEO-03501
4-[(2-Cyanoethyl)methylamino]benzaldehyde[94-21-3]GEO-02609
5-Cyano-2-fluorobenzene-1-sulfonyl chloride[1101120-80-2]GEO-04128
5-Cyano-2-fluoro-3-methylpyridineStructure of 5-Cyano-2-fluoro-3-methylpyridine[261625-67-6]GEO-00835
(E)-2-Cyano-3-(3-fluorophenyl)acrylic acidN/AGEO-03544
(4-Cyano-2-fluorophenyl)methanesulfonyl chloride[1258640-95-7]GEO-03058
(2-Cyano-4-fluorophenyl)methanesulfonyl chloride[1258652-29-7]GEO-03060
(E)-2-Cyano-3-(5-hexylthiophen-2-yl)acrylic acidN/AGEO-03511
2-Cyano-6-hydroxybenzothiazole[939-69-5]GEO-00837
a-Cyano-4-hydroxycinnamic acid[28166-41-8]GEO-00838
alpha-Cyano-4-hydroxycinnamic acid butylamine salt[355011-53-9]GEO-03790
2-Cyano-6-methoxybenzothiazole[943-03-3]GEO-00839
(E)-2-Cyano-3-(5-(4-methoxyphenyl)thiophen-2-yl)acrylic acidN/AGEO-03590
3-Cyano-6-methyl-2-pyridoneStructure of 3-Cyano-6-methyl-2-pyridone[4241-27-4]GEO-00844
Cyanomethyl-2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside[61145-39-9]GEO-04234
4-Cyano-3-nitrobenzoic acid[153775-42-9]GEO-02516
3-Cyanophenyl isocyanate[16413-26-6]GEO-00847
4-Cyanophenyl isothiocyanate[2719-32-6]GEO-03414
(4-Cyanophenyl)methanesulfonyl chloride[56105-99-8]GEO-03057
(2-Cyanophenyl)methanesulfonyl chloride[51045-34-2]GEO-03059
N-(3-Cyanophenyl)pyrrole[175134-98-2]GEO-00848
3-Cyano-1H-pyrazole-4-carboxylic acid methylesterStructure of 3-Cyano-1H-pyrazole-4-carboxylic acid methylester[33090-69-6]GEO-00850
5-Cyano-2-thiophenecarboxaldehyde[21512-16-3]GEO-00851
3,5-DibromoisonicotinonitrileStructure of 3,5-Dibromoisonicotinonitrile[870244-34-1]GEO-03678
4,5-Dicyanoimidazole[1122-28-7]GEO-01018
4-(Diethylamino)butanenitrile[5336-75-4]GEO-01033
2-(2,6-Difluoro-4-methoxybenzylidene)malononitrileN/AGEO-03502
4-(2,6-Difluoro-4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03504
2-(2-(Dimethylamino)-6-fluoro-4-methoxybenzylidene)malononitrileN/AGEO-03495
2,6-Dimethyl-4-(3-phenoxyphenyl)-1,4-dihydropyridine-3,5-dicarbonitrileN/AGEO-03605
4-(4-Ethoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03585
3-(Ethylamino)propionitrileStructure of 3-(Ethylamino)propionitrile[21539-47-9]GEO-01315
(E)-Ethyl 3-(3-bromopyridin-4-yl)-2-cyanoacrylateStructure of (E)-Ethyl 3-(3-bromopyridin-4-yl)-2-cyanoacrylate[]GEO-03649
(E)-Ethyl 2-cyano-3-(1H-imidazol-4-yl)acrylateStructure of (E)-Ethyl 2-cyano-3-(1H-imidazol-4-yl)acrylate[]GEO-03647
(Z)-Ethyl 2-cyano-3-(2-methyl-1H-indol-7-yl)acrylateStructure of (Z)-Ethyl 2-cyano-3-(2-methyl-1H-indol-7-yl)acrylate[]GEO-03636
Ethyl phenylcyanoacetate[4553-07-5]GEO-01372
2-Fluoro-6-methylbenzonitrile[198633-76-0]GEO-02692
4-(4-Fluorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrileN/AGEO-03557
4-(3-Fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03530
4-(4-Fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03554
3-HexyloxypropiononitrileStructure of 3-Hexyloxypropiononitrile[5327-02-6]GEO-01494
2-((5-Hexylthiophen-2-yl)methylene)malononitrileN/AGEO-03509
4-(1H-Imidazol-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileStructure of 4-(1H-Imidazol-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile[]GEO-03644
4-Isobutyl-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileStructure of 4-Isobutyl-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile[]GEO-03628
4-(Isocyanatomethyl)benzonitrileStructure of 4-(Isocyanatomethyl)benzonitrile[1205556-81-5]GEO-03844
4-Isocyanato-2-trifluoromethylbenzonitrileStructure of 4-Isocyanato-2-trifluoromethylbenzonitrile[143782-18-7]GEO-04161
(Z)-2-Isocyano-3-(5-(pyridin-2-ylthio)furan-2-yl)acrylonitrileN/AGEO-03486
5-(4-Methoxyphenyl)thiophene-2-carbonitrileN/AGEO-03594
2-((5-(4-Methoxyphenyl)thiophen-2-yl)methylene)malononitrileN/AGEO-03579
4-(2-Methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03598
(E)-Methyl 3-(5-bromo-2-fluorophenyl)-2-cyanoacrylateStructure of (E)-Methyl 3-(5-bromo-2-fluorophenyl)-2-cyanoacrylate[]GEO-03626
(E)-Methyl 3-(3-bromopyridin-4-yl)-2-cyanoacrylateN/AGEO-03565
(E)-Methyl 3-(6-bromopyridin-2-yl)-2-cyanoacrylateN/AGEO-03512
(E)-Methyl 3-(2-chloro-4-iodopyridin-3-yl)-2-cyanoacrylateStructure of (E)-Methyl 3-(2-chloro-4-iodopyridin-3-yl)-2-cyanoacrylate[]GEO-03668
(E)-Methyl 3-(3-chloro-4-methoxyphenyl)-2-cyanoacrylateN/AGEO-03611
(E)-Methyl 3-(5-(3-chloro-4-methoxyphenyl)furan-2-yl)-2-cyanoacrylateStructure of (E)-Methyl 3-(5-(3-chloro-4-methoxyphenyl)furan-2-yl)-2-cyanoacrylate[]GEO-03643
(E)-Methyl 2-cyano-3-(5-hexylthiophen-2-yl)acrylateN/AGEO-03507
(E)-Methyl 2-cyano-3-(1H-imidazol-4-yl)acrylateStructure of (E)-Methyl 2-cyano-3-(1H-imidazol-4-yl)acrylate[]GEO-03648
(E)-Methyl 2-cyano-3-(2-methoxyphenyl)acrylateN/AGEO-03600
(E)-Methyl 2-cyano-3-(5-(4-methoxyphenyl)thiophen-2-yl)acrylateN/AGEO-03586
(E)-Methyl 2-cyano-3-(5-methylfuran-2-yl)acrylateN/AGEO-03576
(Z)-Methyl 2-cyano-3-(2-methyl-1H-indol-7-yl)acrylateStructure of (Z)-Methyl 2-cyano-3-(2-methyl-1H-indol-7-yl)acrylate[]GEO-03659
(E)-Methyl 2-cyano-3-(6-methylpyridin-3-yl)acrylateStructure of (E)-Methyl 2-cyano-3-(6-methylpyridin-3-yl)acrylate[]GEO-03623
(E)-Methyl 2-cyano-3-(2-methylpyridin-3-yl)acrylateStructure of (E)-Methyl 2-cyano-3-(2-methylpyridin-3-yl)acrylate[]GEO-03664
(E)-Methyl 2-cyano-3-(3-methylpyridin-2-yl)acrylateN/AGEO-03490
(E)-Methyl 2-cyano-3-(5-methylpyridin-2-yl)acrylateN/AGEO-03535
(E)-Methyl 2-cyano-3-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)acrylateN/AGEO-03525
(E)-Methyl 2-cyano-3-(pyridin-2-yl)acrylateN/AGEO-03603
(Z)-Methyl 2-cyano-3-(5-(pyridin-2-ylthio)furan-2-yl)acrylateN/AGEO-03485
(Z)-Methyl 2-cyano-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)acrylateN/AGEO-03496
(E)-Methyl 2-cyano-3-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)acrylateN/AGEO-03546
(E)-Methyl 2-cyano-3-(thiophen-3-yl)acrylateStructure of (E)-Methyl 2-cyano-3-(thiophen-3-yl)acrylate[]GEO-03625
2-((5-Methylfuran-2-yl)methylene)malononitrile[81020-79-3]GEO-03572
2-((2-Methyl-1H-indol-7-yl)methylene)malononitrileStructure of 2-((2-Methyl-1H-indol-7-yl)methylene)malononitrile[]GEO-03658
2-Methyl-6-pentafluoroethyl-5-trifluoromethylpyrimidine-4-carbonitrileStructure of 2-Methyl-6-pentafluoroethyl-5-trifluoromethylpyrimidine-4-carbonitrileN/AGEO-02526
6-Methyl-2-pyridinecarbonitrileStructure of 6-Methyl-2-pyridinecarbonitrile[1620-75-3]GEO-01725
2-((5-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)methylene)malononitrileN/AGEO-03523
5-Methylthiophene-2-carbonitrileStructure of 5-Methylthiophene-2-carbonitrile[72835-25-7]GEO-01953
3-Methylthiophene-2-carbonitrileStructure of 3-Methylthiophene-2-carbonitrile[55406-13-8]GEO-02888
2-(6-Nitro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)acetonitrileStructure of 2-(6-Nitro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)acetonitrile[]GEO-03680
PentafluorobenzonitrileStructure of Pentafluorobenzonitrile[773-82-0]GEO-03210
4-PentenenitrileStructure of 4-Pentenenitrile[592-51-8]GEO-02090
3-PentoxypropionitrileStructure of 3-Pentoxypropionitrile[16728-47-5]GEO-02092
3-(2-Phenoxyethoxy)propiononitrileStructure of 3-(2-Phenoxyethoxy)propiononitrile[6328-54-7]GEO-02100
Pyrrole-2-carbonitrileStructure of Pyrrole-2-carbonitrile[4513-94-4]GEO-02199
1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile[4414-89-5]GEO-03547
2-((1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)methylene)malononitrileN/AGEO-03550
1,2-Thiazole-3-carbonitrileStructure of 1,2-Thiazole-3-carbonitrile[1452-17-1]GEO-04061
2-ThiopheneacetonitrileStructure of 2-Thiopheneacetonitrile[20893-30-5]GEO-02310
6-(Trifluoromethyl)nicotinonitrileStructure of 6-(Trifluoromethyl)nicotinonitrile[216431-85-5]GEO-02389
2,7,7-Trimethyl-4-(5-methylfuran-2-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03599
2,7,7-Trimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03524