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Nitriles


Nitriles are a class of organic compounds that contain at least one nitrile (cyano) function group. The main methods for producing nitriles in industry are ammoxidation and hydrocyanation. Other common preparations involve reactions of organic halides with cyanide salts, dehydration of aldoximes and amides, Sandmeyer reaction of aromatic diazonium salts. Nitrile groups in organic compounds can undergo a variety of reactions such as hydrolysis to first give carboxamides and then carboxylic acids, reduction to amines and alkyl nitriles can be deprotonated to nitrile anions that can alkylate a wide range of electrophiles. They also undergo nucleophilic addition reactions with organozinc compounds (Blaise reaction), alcohols (Pinner reaction) and amines. They are found in many useful compounds, including methyl cyanoacrylate in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves.

Product nameStructureCAS#G-code
New2-Chloro-3-methoxybenzonitrileStructure of 2-Chloro-3-methoxybenzonitrile[853331-52-9]GEO-04562
(2-Cyano-4-fluorophenyl)methanesulfonyl chloride[1258652-29-7]GEO-03060
(2-Cyanophenyl)methanesulfonyl chloride[51045-34-2]GEO-03059
(2E)-3-[2,2′-Bithiophen]-5-yl-2-cyano-2-propenoic acidStructure of (2E)-3-[2,2'-Bithiophen]-5-yl-2-cyano-2-propenoic acid[2138319-65-8]GEO-04262
(4-Cyano-2-fluorophenyl)methanesulfonyl chloride[1258640-95-7]GEO-03058
(4-Cyanophenyl)methanesulfonyl chloride[56105-99-8]GEO-03057
(E)-2-Cyano-3-(2-(dimethylamino)-6-fluoro-4-methoxyphenyl)acrylic acidN/AGEO-03501
(E)-2-Cyano-3-(3-fluorophenyl)acrylic acidN/AGEO-03544
(E)-2-Cyano-3-(5-(4-methoxyphenyl)thiophen-2-yl)acrylic acidN/AGEO-03590
(E)-2-Cyano-3-(5-hexylthiophen-2-yl)acrylic acidN/AGEO-03511
(E)-3-(3-Chloro-4-methoxyphenyl)-2-cyanoacrylic acidStructure of (E)-3-(3-Chloro-4-methoxyphenyl)-2-cyanoacrylic acid[]GEO-03618
(E)-3-(5-(4-Bromo-2-fluorophenyl)furan-2-yl)-2-cyanoacrylic acidStructure of (E)-3-(5-(4-Bromo-2-fluorophenyl)furan-2-yl)-2-cyanoacrylic acid[]GEO-03638
(E)-3-(5-Bromo-2-fluorophenyl)-2-cyanoacrylic acidStructure of (E)-3-(5-Bromo-2-fluorophenyl)-2-cyanoacrylic acid[]GEO-03632
(E)-Ethyl 2-cyano-3-(1H-imidazol-4-yl)acrylateStructure of (E)-Ethyl 2-cyano-3-(1H-imidazol-4-yl)acrylate[]GEO-03647
(E)-Ethyl 3-(3-bromopyridin-4-yl)-2-cyanoacrylateStructure of (E)-Ethyl 3-(3-bromopyridin-4-yl)-2-cyanoacrylate[]GEO-03649
(E)-Methyl 2-cyano-3-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)acrylateN/AGEO-03546
(E)-Methyl 2-cyano-3-(1H-imidazol-4-yl)acrylateStructure of (E)-Methyl 2-cyano-3-(1H-imidazol-4-yl)acrylate[]GEO-03648
(E)-Methyl 2-cyano-3-(2-methoxyphenyl)acrylateN/AGEO-03600
(E)-Methyl 2-cyano-3-(2-methylpyridin-3-yl)acrylateStructure of (E)-Methyl 2-cyano-3-(2-methylpyridin-3-yl)acrylate[]GEO-03664
(E)-Methyl 2-cyano-3-(3-methylpyridin-2-yl)acrylateN/AGEO-03490
(E)-Methyl 2-cyano-3-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)acrylateN/AGEO-03525
(E)-Methyl 2-cyano-3-(5-(4-methoxyphenyl)thiophen-2-yl)acrylateN/AGEO-03586
(E)-Methyl 2-cyano-3-(5-hexylthiophen-2-yl)acrylateN/AGEO-03507
(E)-Methyl 2-cyano-3-(5-methylfuran-2-yl)acrylateN/AGEO-03576
(E)-Methyl 2-cyano-3-(5-methylpyridin-2-yl)acrylateN/AGEO-03535
(E)-Methyl 2-cyano-3-(6-methylpyridin-3-yl)acrylateStructure of (E)-Methyl 2-cyano-3-(6-methylpyridin-3-yl)acrylate[]GEO-03623
(E)-Methyl 2-cyano-3-(pyridin-2-yl)acrylateN/AGEO-03603
(E)-Methyl 2-cyano-3-(thiophen-3-yl)acrylateStructure of (E)-Methyl 2-cyano-3-(thiophen-3-yl)acrylate[]GEO-03625
(E)-Methyl 3-(2-chloro-4-iodopyridin-3-yl)-2-cyanoacrylateStructure of (E)-Methyl 3-(2-chloro-4-iodopyridin-3-yl)-2-cyanoacrylate[]GEO-03668
(E)-Methyl 3-(3-bromopyridin-4-yl)-2-cyanoacrylateN/AGEO-03565
(E)-Methyl 3-(3-chloro-4-methoxyphenyl)-2-cyanoacrylateN/AGEO-03611
(E)-Methyl 3-(5-(3-chloro-4-methoxyphenyl)furan-2-yl)-2-cyanoacrylateStructure of (E)-Methyl 3-(5-(3-chloro-4-methoxyphenyl)furan-2-yl)-2-cyanoacrylate[]GEO-03643
(E)-Methyl 3-(5-bromo-2-fluorophenyl)-2-cyanoacrylateStructure of (E)-Methyl 3-(5-bromo-2-fluorophenyl)-2-cyanoacrylate[]GEO-03626
(E)-Methyl 3-(6-bromopyridin-2-yl)-2-cyanoacrylateN/AGEO-03512
(Z)-2-Isocyano-3-(5-(pyridin-2-ylthio)furan-2-yl)acrylonitrileN/AGEO-03486
(Z)-Ethyl 2-cyano-3-(2-methyl-1H-indol-7-yl)acrylateStructure of (Z)-Ethyl 2-cyano-3-(2-methyl-1H-indol-7-yl)acrylate[]GEO-03636
(Z)-Methyl 2-cyano-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)acrylateN/AGEO-03496
(Z)-Methyl 2-cyano-3-(2-methyl-1H-indol-7-yl)acrylateStructure of (Z)-Methyl 2-cyano-3-(2-methyl-1H-indol-7-yl)acrylate[]GEO-03659
(Z)-Methyl 2-cyano-3-(5-(pyridin-2-ylthio)furan-2-yl)acrylateN/AGEO-03485
1,2-Thiazole-3-carbonitrileStructure of 1,2-Thiazole-3-carbonitrile[1452-17-1]GEO-04061
1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile[4414-89-5]GEO-03547
2-((1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)methylene)malononitrileN/AGEO-03550
2-((2-Chloro-4-iodopyridin-3-yl)methylene)malononitrileStructure of 2-((2-Chloro-4-iodopyridin-3-yl)methylene)malononitrile[]GEO-03645
2-((2-Methyl-1H-indol-7-yl)methylene)malononitrileStructure of 2-((2-Methyl-1H-indol-7-yl)methylene)malononitrile[]GEO-03658
2-((4-Bromothiophen-3-yl)methylene)malononitrileStructure of 2-((4-Bromothiophen-3-yl)methylene)malononitrile[]GEO-03663
2-((5-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)methylene)malononitrileN/AGEO-03523
2-((5-(3-Chloro-4-methoxyphenyl)furan-2-yl)methylene)malononitrileStructure of 2-((5-(3-Chloro-4-methoxyphenyl)furan-2-yl)methylene)malononitrile[]GEO-03642
2-((5-(4-Methoxyphenyl)thiophen-2-yl)methylene)malononitrileN/AGEO-03579
2-((5-Hexylthiophen-2-yl)methylene)malononitrileN/AGEO-03509
2-((5-Methylfuran-2-yl)methylene)malononitrile[81020-79-3]GEO-03572
2-(2-(Dimethylamino)-6-fluoro-4-methoxybenzylidene)malononitrileN/AGEO-03495
2-(2,6-Difluoro-4-methoxybenzylidene)malononitrileN/AGEO-03502
2-(3-Chloro-4-methoxybenzylidene)malononitrileN/AGEO-03596
2-(5-Bromo-2-fluorobenzylidene)malononitrileStructure of 2-(5-Bromo-2-fluorobenzylidene)malononitrile[]GEO-03627
2-(6-Nitro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)acetonitrileStructure of 2-(6-Nitro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)acetonitrile[]GEO-03680
2-Chloro-4-iodo-3-pyridinecarbonitrile[1171919-75-7]GEO-03264
2-Chloro-6-methylbenzonitrileStructure of 2-Chloro-6-methylbenzonitrile[6575-09-3]GEO-00710
2-Chlorothiazole-5-carbonitrile[51640-36-9]GEO-03608
2-Cyano-6-hydroxybenzothiazole[939-69-5]GEO-00837
2-Cyano-6-methoxybenzothiazole[943-03-3]GEO-00839
2-Fluoro-6-methylbenzonitrile[198633-76-0]GEO-02692
2-Methyl-6-pentafluoroethyl-5-trifluoromethylpyrimidine-4-carbonitrileStructure of 2-Methyl-6-pentafluoroethyl-5-trifluoromethylpyrimidine-4-carbonitrileN/AGEO-02526
2-ThiopheneacetonitrileStructure of 2-Thiopheneacetonitrile[20893-30-5]GEO-02310
2,6-Dimethyl-4-(3-phenoxyphenyl)-1,4-dihydropyridine-3,5-dicarbonitrileN/AGEO-03605
2,7,7-Trimethyl-4-(5-((5-methyl-1,3,4-thiadiazol-2-yl)thio)furan-2-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03524
2,7,7-Trimethyl-4-(5-methylfuran-2-yl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03599
3-(2-Phenoxyethoxy)propiononitrileStructure of 3-(2-Phenoxyethoxy)propiononitrile[6328-54-7]GEO-02100
3-(Ethylamino)propionitrileStructure of 3-(Ethylamino)propionitrile[21539-47-9]GEO-01315
3-Chloro-4-methylbenzonitrileStructure of 3-Chloro-4-methylbenzonitrile[21423-81-4]GEO-04031
3-Chloroisonicotinonitrile[68325-15-5]GEO-03482
3-Cyano-1H-pyrazole-4-carboxylic acid methylesterStructure of 3-Cyano-1H-pyrazole-4-carboxylic acid methylester[33090-69-6]GEO-00850
3-Cyano-6-methyl-2-pyridoneStructure of 3-Cyano-6-methyl-2-pyridone[4241-27-4]GEO-00844
3-Cyanophenyl isocyanate[16413-26-6]GEO-00847
3-HexyloxypropiononitrileStructure of 3-Hexyloxypropiononitrile[5327-02-6]GEO-01494
3-Methylthiophene-2-carbonitrileStructure of 3-Methylthiophene-2-carbonitrile[55406-13-8]GEO-02888
3-n-ButoxypropionitrileStructure of 3-n-Butoxypropionitrile[6959-71-3]GEO-00607
3-PentoxypropionitrileStructure of 3-Pentoxypropionitrile[16728-47-5]GEO-02092
3,5-DibromoisonicotinonitrileStructure of 3,5-Dibromoisonicotinonitrile[870244-34-1]GEO-03678
3′-Bromo-2,6-dimethyl-1,4-dihydro-[4,4′-bipyridine]-3,5-dicarbonitrileN/AGEO-03570
4-(1H-Imidazol-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileStructure of 4-(1H-Imidazol-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile[]GEO-03644
4-(2-Methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03598
4-(2,6-Difluoro-4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03504
4-(3-Bromopyridin-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03569
4-(3-Chloro-4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrileStructure of 4-(3-Chloro-4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile[]GEO-03614
4-(3-Chloro-4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileStructure of 4-(3-Chloro-4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile[]GEO-03613
4-(3-Fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03530
4-(4-(tert-Butyl)phenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03604
4-(4-Ethoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03585
4-(4-Fluorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrileN/AGEO-03557
4-(4-Fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileN/AGEO-03554
4-(5-(4-Bromo-2-fluorophenyl)furan-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrileStructure of 4-(5-(4-Bromo-2-fluorophenyl)furan-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile[]GEO-03637
4-(5-Bromo-2-fluorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrileStructure of 4-(5-Bromo-2-fluorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile[]GEO-03619
4-(5-Bromo-2-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileStructure of 4-(5-Bromo-2-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile[]GEO-03622
4-(Diethylamino)butanenitrile[5336-75-4]GEO-01033
4-(Isocyanatomethyl)benzonitrileStructure of 4-(Isocyanatomethyl)benzonitrile[1205556-81-5]GEO-03844
4-[(2-Cyanoethyl)methylamino]benzaldehyde[94-21-3]GEO-02609
4-Bromo-1H-pyrazole-3-carbonitrileStructure of 4-Bromo-1H-pyrazole-3-carbonitrile[288246-16-2]GEO-00562
4-Cyano-3-nitrobenzoic acid[153775-42-9]GEO-02516
4-Cyanobenzenesulfonyl chloride[49584-26-1]GEO-04025
4-Cyanophenyl isothiocyanate[2719-32-6]GEO-03414
4-Isobutyl-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrileStructure of 4-Isobutyl-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile[]GEO-03628
4-Isocyanato-2-trifluoromethylbenzonitrileStructure of 4-Isocyanato-2-trifluoromethylbenzonitrile[143782-18-7]GEO-04161
4-PentenenitrileStructure of 4-Pentenenitrile[592-51-8]GEO-02090
4,5-Dicyanoimidazole[1122-28-7]GEO-01018
5-(4-Methoxyphenyl)thiophene-2-carbonitrileN/AGEO-03594
5-Acetyl-2-amino-4-(2-furanyl)-6-methyl-4H-pyran-3-carbonitrileStructure of 5-Acetyl-2-amino-4-(2-furanyl)-6-methyl-4H-pyran-3-carbonitrile[105263-08-9]GEO-00016
5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrileStructure of 5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile[105263-07-8]GEO-00017
5-Acetyl-2-amino-6-methyl-4-phenyl-4H-pyran-3-carbonitrileStructure of 5-Acetyl-2-amino-6-methyl-4-phenyl-4H-pyran-3-carbonitrile[89809-89-2]GEO-00018
5-Amino-3-phenyl-isothiazole-4-carbonitrileStructure of 5-Amino-3-phenyl-isothiazole-4-carbonitrile[88009-93-2]GEO-03690
5-Bromothiophene-2-carbonitrileStructure of 5-Bromothiophene-2-carbonitrile[2160-62-5]GEO-04253
5-ChlorovaleronitrileStructure of 5-Chlorovaleronitrile[6280-87-1]GEO-00825
5-Cyano-2-fluoro-3-methylpyridineStructure of 5-Cyano-2-fluoro-3-methylpyridine[261625-67-6]GEO-00835
5-Cyano-2-fluorobenzene-1-sulfonyl chloride[1101120-80-2]GEO-04128
5-Cyano-2-thiophenecarboxaldehyde[21512-16-3]GEO-00851
5-Methylthiophene-2-carbonitrileStructure of 5-Methylthiophene-2-carbonitrile[72835-25-7]GEO-01953
6-(Trifluoromethyl)nicotinonitrileStructure of 6-(Trifluoromethyl)nicotinonitrile[216431-85-5]GEO-02389
6-Methyl-2-pyridinecarbonitrileStructure of 6-Methyl-2-pyridinecarbonitrile[1620-75-3]GEO-01725
a-Cyano-4-hydroxycinnamic acid[28166-41-8]GEO-00838
alpha-Cyano-4-hydroxycinnamic acid butylamine salt[355011-53-9]GEO-03790
Cyanomethyl-2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside[61145-39-9]GEO-04234
Ethyl phenylcyanoacetate[4553-07-5]GEO-01372
N-(3-Cyanophenyl)pyrrole[175134-98-2]GEO-00848
N-Cyanoacetylurethane[6629-04-5]GEO-00827
PentafluorobenzonitrileStructure of Pentafluorobenzonitrile[773-82-0]GEO-03210
Pyrrole-2-carbonitrileStructure of Pyrrole-2-carbonitrile[4513-94-4]GEO-02199