Carbamic acid derivatives / Carbamates / Carbamoyl chlorides / Thiocarbamoyl chlorides

It is a class of compounds with amino carboxylic (or amino thiocarboxylic) functional group. Carbamic acids are generally unstable at room temperature, reverting to the parent amine and carbon dioxide. Carbamate esters are generally stable at room temperature. They are prepared by reaction of carbamoyl chlorides with alcohols, the addition of alcohols to isocyanates, and the reaction of carbonate esters with ammonia. Carbamate esters often serve as a protecting group for amines, which can be later hydrolyse to carbamic acid that lose carbon dioxide to yield desired amine.