{"id":33806,"date":"2025-06-17T08:56:07","date_gmt":"2025-06-17T06:56:07","guid":{"rendered":"https:\/\/georganics.sk\/research\/asymmetric-formal-synthesis-of-pyrenolide-d\/"},"modified":"2025-06-30T12:55:02","modified_gmt":"2025-06-30T10:55:02","slug":"asymmetric-formal-synthesis-of-pyrenolide-d","status":"publish","type":"page","link":"https:\/\/georganics.sk\/fr\/research\/asymmetric-formal-synthesis-of-pyrenolide-d\/","title":{"rendered":"Asymmetric Formal Synthesis of (+)-Pyrenolide D"},"content":{"rendered":"<p>Une synth\u00e8se formelle asym\u00e9trique concise du (+)-pyr\u00e9nolide D \u00e0 partir du (E)-crotonald\u00e9hyde est d\u00e9crite. Les \u00e9tapes cl\u00e9s comprennent une dihydroxylation \u00e9nantios\u00e9lective de Sharpless de l&rsquo;hex-4-en-1-yn-3-ol prot\u00e9g\u00e9 et une oxycarbonylation hautement diast\u00e9r\u00e9os\u00e9lective <a href=\"https:\/\/georganics.sk\/fr\/special-offers\/palladium-catalysts\/\" target=\"_blank\" rel=\"noopener\">catalys\u00e9e au palladium<\/a> du (2R,3S,4S)-hex-5-\u00e8ne-2,3,4-triol en utilisant le pentacarbonyle de fer comme source de monoxyde de carbone.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Une synth\u00e8se formelle asym\u00e9trique concise du (+)-pyr\u00e9nolide D \u00e0 partir du (E)-crotonald\u00e9hyde est d\u00e9crite. Les \u00e9tapes cl\u00e9s comprennent une dihydroxylation \u00e9nantios\u00e9lective de Sharpless de l&rsquo;hex-4-en-1-yn-3-ol prot\u00e9g\u00e9 et une oxycarbonylation hautement diast\u00e9r\u00e9os\u00e9lective catalys\u00e9e au palladium du (2R,3S,4S)-hex-5-\u00e8ne-2,3,4-triol en utilisant le pentacarbonyle de fer comme source de monoxyde de carbone.<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":18920,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-randpost.php","meta":{"_acf_changed":false,"footnotes":""},"folder":[],"class_list":["post-33806","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Asymmetric Formal Synthesis of (+)-Pyrenolide D - Georganics<\/title>\n<meta name=\"description\" content=\"Explorez la synth\u00e8se formelle asym\u00e9trique du (+)-pyr\u00e9nolide D \u00e0 partir du (E)-crotonald\u00e9hyde avec des \u00e9tapes de synth\u00e8se cl\u00e9s.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/georganics.sk\/fr\/research\/asymmetric-formal-synthesis-of-pyrenolide-d\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Asymmetric Formal Synthesis of (+)-Pyrenolide D\" \/>\n<meta property=\"og:description\" content=\"Explorez la synth\u00e8se formelle asym\u00e9trique du (+)-pyr\u00e9nolide D \u00e0 partir du (E)-crotonald\u00e9hyde avec des \u00e9tapes de synth\u00e8se cl\u00e9s.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/georganics.sk\/fr\/research\/asymmetric-formal-synthesis-of-pyrenolide-d\/\" \/>\n<meta property=\"og:site_name\" content=\"Georganics\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-30T10:55:02+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/georganics.sk\\\/fr\\\/research\\\/asymmetric-formal-synthesis-of-pyrenolide-d\\\/\",\"url\":\"https:\\\/\\\/georganics.sk\\\/fr\\\/research\\\/asymmetric-formal-synthesis-of-pyrenolide-d\\\/\",\"name\":\"Asymmetric Formal Synthesis of (+)-Pyrenolide D - 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