{"id":33798,"date":"2025-06-06T13:42:58","date_gmt":"2025-06-06T11:42:58","guid":{"rendered":"https:\/\/georganics.sk\/research\/a-universal-strategy-for-synthesis-of-agropyrenol-family-total-synthesis-of-agropyrenol-sordarial-and-heterocornol-a-and-b\/"},"modified":"2025-06-27T14:43:40","modified_gmt":"2025-06-27T12:43:40","slug":"a-universal-strategy-for-synthesis-of-agropyrenol-family-total-synthesis-of-agropyrenol-sordarial-and-heterocornol-a-and-b","status":"publish","type":"page","link":"https:\/\/georganics.sk\/fr\/research\/a-universal-strategy-for-synthesis-of-agropyrenol-family-total-synthesis-of-agropyrenol-sordarial-and-heterocornol-a-and-b\/","title":{"rendered":"A Universal Strategy for Synthesis of Agropyrenol Family. Total Synthesis of Agropyrenol, Sordarial, and Heterocornol A and B"},"content":{"rendered":"<div class=\"art-abstract in-tab hypothesis_container ai-optimize-introduction\">Une strat\u00e9gie divergente pour la synth\u00e8se de polyc\u00e9tides naturels a \u00e9t\u00e9 con\u00e7ue. Cette voie de synth\u00e8se a permis des alt\u00e9rations chimiques conduisant \u00e0 tous les st\u00e9r\u00e9oisom\u00e8res de l&rsquo;agropyr\u00e9nol naturel <strong>1<\/strong>, du sordariol <strong>2<\/strong> et de l&rsquo;h\u00e9t\u00e9rocornol B <strong>4<\/strong>. Les \u00e9tapes cl\u00e9s impliquent la d\u00e9sym\u00e9trisation du divinylcarbinol par <a href=\"https:\/\/georganics.sk\/fr\/services\/#chemicalsyntheticcapabilities\" target=\"_blank\" rel=\"noopener\">\u00e9poxydation Sharpless et couplage de Heck<\/a> asym\u00e9trique d&rsquo;un partenaire aromatique facilement disponible et d&rsquo;un alc\u00e8ne chiral pr\u00e9par\u00e9. La polyvalence de la m\u00e9thode de synth\u00e8se a \u00e9t\u00e9 d\u00e9montr\u00e9e sur la pr\u00e9paration de l&rsquo;h\u00e9t\u00e9rocornol A <strong>3<\/strong> et du sordariol <strong>5<\/strong>. Les configurations absolues et relatives des compos\u00e9s naturels pr\u00e9par\u00e9s <strong>2<\/strong>\u00b71\/3C6H12 et <strong>4<\/strong> ont \u00e9t\u00e9 confirm\u00e9es et attribu\u00e9es par analyse aux rayons X sur monocristal.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Une strat\u00e9gie divergente pour la synth\u00e8se de polyc\u00e9tides naturels a \u00e9t\u00e9 con\u00e7ue. Cette voie de synth\u00e8se a permis des alt\u00e9rations chimiques conduisant \u00e0 tous les st\u00e9r\u00e9oisom\u00e8res de l&rsquo;agropyr\u00e9nol naturel 1, du sordariol 2 et de l&rsquo;h\u00e9t\u00e9rocornol B 4. Les \u00e9tapes cl\u00e9s impliquent la d\u00e9sym\u00e9trisation du divinylcarbinol par \u00e9poxydation Sharpless et couplage de Heck asym\u00e9trique d&rsquo;un [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":18920,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-randpost.php","meta":{"_acf_changed":false,"footnotes":""},"folder":[],"class_list":["post-33798","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Total Synthesis of Agropyrenol Family Research Findings<\/title>\n<meta name=\"description\" content=\"Explorez la synth\u00e8se totale de la famille des agropyr\u00e9nols, en pr\u00e9sentant des strat\u00e9gies innovantes et des techniques de production de st\u00e9r\u00e9oisom\u00e8res.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/georganics.sk\/fr\/research\/a-universal-strategy-for-synthesis-of-agropyrenol-family-total-synthesis-of-agropyrenol-sordarial-and-heterocornol-a-and-b\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A Universal Strategy for Synthesis of Agropyrenol Family. 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